Patent丨Bionic Intestinal Organ-on-a-Chip from Jiyan Biotech

Jiyan Biotech has been granted a patent titled "A Bionic Intestinal Organ-on-a-Chip" (Authorization Announcement No. CN221720838U), with an application date of August 2024, which can rapidly cultivate a variety of bionic intestinal microstructures.

The patent abstract reveals that this utility model pertains to a bionic intestinal organ - on - a - chip, comprising a chip body with a hydrogel chamber. The hydrogel chamber measures 0.5 - 3 cm in length, 0.5 - 3 cm in width, and 0.1 - 3 mm in height. It connects to a hydrogel inlet at one end and a hydrogel outlet at the other.

Inside the chamber, a patterned 3D hydrogel scaffold is formed from photocurable hydrogel via a patterning mask. A cell seeding channel links to the chamber for cell inoculation into the 3D scaffold. Multiple fence - like microstructures on the chamber's sidewall connect it to two culture medium channels, each 0.5 - 4 cm long. This utility model enables rapid cultivation of diverse bionic intestinal microstructures.